HSP27 Alleviates Cardiac Aging in Mice via a Mechanism Involving Antioxidation and Mitophagy Activation

Figure 7

HSP27 decreases the levels of ubiquitin-conjugated protein in the hearts of old mice. The hearts were collected from 24-month-old mice. Protein extracts were prepared for immunoblot analysis against ubiquitin (a). The Coomassie blue-stained gel served as loading control (b). versus WT controls. per group.

(a)

(b)

(c)