Hydrogen Sulfide Regulates the [Ca²⁺]_i Level in the Primary Medullary Neurons

Figure 5

The effect of NaHS on in the primarily cultured medullary neurons in Ca²⁺-free solution or in the presence of L-type and/or T-type Ca²⁺ channels inhibitors. ((a)–(c)) Typical suppression of level induced by NaHS in EGTA-treated Ca²⁺-free solution (a) or in normal Ca²⁺ containing HBSS with or without nifedipine (10 μM, (b)), nimodipine (10 μM, (c)), and mibefradil (2 μM, (d)). (e) Group data showed that the effects of NaHS were attenuated by EGTA-Ca²⁺-free solution and suppressed by nifedipine, nimodipine, or mibefradil. versus Control; versus NaHS group; versus NaHS group. in each group.

(a)

(b)

(c)

(d)

(e)