Review Article

NRF2, a Key Regulator of Antioxidants with Two Faces towards Cancer

Figure 2

Domain structure of NRF2 and KEAP1 proteins. bZIP: basic leucine zipper, NTR: N-terminal region, BTB: Broad Complex, Tramtrack, and Bric-a-Brac, IVR: intervening region, DGR: double glycine repeat (=Kelch), and CTR: carboxyl terminal region.