Epigallocatechin-3-gallate Attenuates Renal Damage by Suppressing Oxidative Stress in Diabetic db/db Mice

Figure 1

Glucose metabolic profile in db/db mice versus control mice. Diabetic db/db mice were treated with or without EGCG for 4 or 8 weeks, and OGTT (glucose, 1 g/kg) were performed. Glucose concentrations (a and c) and the AUC of OGTT (b and d) were shown. Normal: nontreated C57BL mice; control: C57BLKS/J db/db nontreated mice; EGCG A, db/db mice treated with EGCG of 50 mg/kg/d; EGCG B, db/db mice treated with EGCG of 100 mg/kg/d; values are means ± SEM. versus normal; and versus control; versus EGCG A. At week 4, in each group; at week 8, in each group.

(a)

(b)

(c)

(d)