Epigallocatechin-3-gallate Attenuates Renal Damage by Suppressing Oxidative Stress in Diabetic db/db Mice

Figure 7

The protein expression of p-ERK1/2 (b), p-P38 MAPK (c), TGF-β1 (d), and α-SMA (e) of HK-2 cell after exposure to Ang II, PD98059, and SB202190. HK-2 cells were pretreated with PD98059 (ERK1/2 inhibitor) and/or SB202190 (p38 MAPK inhibitor) (all 10 mM) for 6 h and then stimulated with Ang II (1 μM) for 24 hours. Values are means ± SEM. and versus control.

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