Review Article

Widening and Elaboration of Consecutive Research into Therapeutic Antioxidant Enzyme Derivatives

Table 1

Some characteristics of SOD-CHS-CAT derivative.

Parameters of bienzyme SOD-CHS-CAT conjugate

Appearance of derivativeWhite-gray powder
Content of protein in preparation5–7%
Specific SOD activity43–47 U SOD/mg preparation
Specific CAT activity70–75 U CAT/mg preparation
Effective dose for intravenous bolus administration in vivo1-2 mg preparation
Recommended dose (according to enzyme activity) for acute injury in vivo80–90 U SOD/kg
145–185 U CAT/kg