Caspase-3 Deletion Promotes Necrosis in Atherosclerotic Plaques of ApoE Knockout Mice

Table 1

Characteristics of Casp3^+/+ApoE^−/− mice and Casp3^−/−ApoE^−/− mice after 16 weeks on western-type diet.

	Casp3^+/+ApoE^−/−	Casp3^−/−ApoE^−/−
General
Body weight (g)	34 ± 1	33 ± 1
Heart weight (mg)	150 ± 3	161 ± 16
Lipids
Total cholesterol (mg/dL)	473 ± 32	423 ± 38
LDL cholesterol (mg/dL)	309 ± 21	258 ± 29
Triglycerides (mg/dL)	114 ± 7	105 ± 18
Cardiac function
EDD LV (mm)	4.2 ± 0.1	4.0 ± 0.2
ESD LV (mm)	2.7 ± 0.1	2.6 ± 0.1
FS (%)	36 ± 2	35 ± 1

Student’s t-test; P > 0.05.