Efficiency of Base Excision Repair of Oxidative DNA Damage and Its Impact on the Risk of Colorectal Cancer in the Polish Population

Table 5

The distribution of genotypes and the analysis of the odds ratio (OR) for gene-gene interactions: 589Lys/Glu EXO1 and 242Pro/Arg PolB in patients with colorectal cancer (CRC) and the control group.

Genotype	Patients	Controls	OR (95% CI)
Lys/Lys-Pro/Pro	24	28	1 (ref.)	—
Lys/Lys-Pro/Arg	20	26	0.897 (0.404–1.994)	0.791
Lys/Lys-Arg/Arg	11	15	0.856 (0.331–2.212)	0.752
Lys/Glu-Pro/Pro	99	51	2.265 (1.193–4.301)	0.011
Lys/Glu-Pro/Arg	81	72	1.313 (0.698–2.467)	0.396
Lys/Glu-Arg/Arg	19	23	0.964 (0.426–2.180)	0.920
Glu/Glu-Pro/Pro	23	42	0.639 (0.303–1.346)	0.238
Glu/Glu-Pro/Arg	22	44	0.583 (0.276–1.232)	0.156
Glu/Glu-Arg/Arg	3	1	—	—