Efficiency of Base Excision Repair of Oxidative DNA Damage and Its Impact on the Risk of Colorectal Cancer in the Polish Population

Table 7

The distribution of genotypes and the analysis of the odds ratio (OR) for gene-gene interactions: 242Pro/Arg PolB and 780Arg/His LIG3 in patients with colorectal cancer (CRC) and the control group.

Genotype	Patients	Controls	OR (95% CI)
Pro/Pro-Arg/Arg	52	56	1 (ref.)	—
Pro/Pro-Arg/His	82	41	2.154 (1.265–3.667)	0.004
Pro/Pro-His/His	12	24	0.539 (0.245–1.185)	0.121
Pro/Arg-Arg/Arg	38	48	0.853 (0.483–1.506)	0.584
Pro/Arg-Arg/His	66	73	0.974 (0.589–1.611)	0.920
Pro/Arg-His/His	19	21	0.974 (0.471–2.015)	1.000
Arg/Arg-Arg/Arg	9	15	0.646 (0.261–1.603)	0.343
Arg/Arg-Arg/His	20	17	1.267 (0.599–2.679)	0.538
Arg/Arg-His/His	4	7	—	—