2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside Promotes Expression of the Longevity Gene Klotho

Table 2

Effect of Polygonum stilbene glucoside on serum calcium and phosphorus levels and alkaline phosphatase activity and bone strength ().

Groups	Serum; calcium	Serum; phosphorus	Alkaline; phosphatase	Femur; BMD	Bone; mineral content	Femur bearing strength
	(mmol/L)	(mmol/L)	(IU/L)	(g/cm^2)	(g/cm^2)	(kg)
SHR (12 w)	2.18 ± 0.14	0.83 ± 0.27	74.1 ± 12.4	0.167 ± 0.019	0.475 ± 0.044	10.60 ± 2.03
SHR (30 w)	1.90 ± 0.	0.51 ± 0.	73.9 ± 29.9	0.219 ± 0.0	0.685 ± 0.0	12.79 ± 1.
SHR (30 w) + THSG	2.11 ± 0.	0.46 ± 0.12	65.2 ± 17.6	0.228 ± 0.014	0.640 ± 0.075	14.19 ± 1.

with 12-week-old SHRs, . with 30-week-old SHRs,