An Explanation of the Underlying Mechanisms for the In Vitro and In Vivo Antiurolithic Activity of Glechoma longituba

Figure 4

Immunohistochemistry of KIM-1 (a) and OPN (b) protein expression in the kidneys. Group 1: control group; group 2: urolithiasis group; and group 3: potassium citrate-treated urolithiasis group. Glechoma longituba was gavaged 220 mg/kg/day, 440 mg/kg/day, and 880 mg/kg/day to groups 4, 5, and 6 via oral tube feeding, respectively (100x).

(a)

(b)