Renalase as a Novel Biomarker for Evaluating the Severity of Hepatic Ischemia-Reperfusion Injury

Figure 3

Augmentation of renalase expression in hepatic I/R injury models and the subsequent decrease induced by antioxidant preinjection. (a) Relative expression of renalase mRNA evaluated by real-time qPCR in livers of mouse models (sham, I/R injury, and I/R injury with antioxidant preinjection, 6 h after reperfusion). (b) Western blot analysis of renalase protein levels in livers of mouse models (sham, I/R injury, and I/R injury with antioxidant preinjection, 6 h after reperfusion). (c) Densitometric analysis of Western blot of renalase in livers of mouse models (sham, I/R injury, and I/R injury with antioxidant preinjection, 6 h after reperfusion). . Data are plotted as the mean ± SD from five independent experiments. Bars indicate the standard deviation of the mean.

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