Inhibition of HSP90 Promotes Neural Stem Cell Survival from Oxidative Stress through Attenuating NF-κB/p65 Activation

Figure 6

Effect of Geldanamycin on the H₂O₂ damaged NSCs. The pretreatment of 0.5 M GA was administrated to NSCs for 1 h, followed by the H₂O₂ induction. The NSCs treated with the vehicle medium were used as control. (a) The cell death of each group of NSCs detected by Hoechst 33342/PI double staining. (b) The cell viability of each group of NSCs by MTT assay. was considered to be significantly different between control and H₂O₂ or between H₂O₂ and DA+H₂O₂ groups. n = 3.

(a)

(b)