Protective Effects of Melatonin on Retinal Inflammation and Oxidative Stress in Experimental Diabetic Retinopathy

Figure 7

Effect of melatonin on NF-κB expression in retinas from diabetic rats. (a) Western blot of cytosolic NF-κB, nuclear NF-κB, IκB, and phosphorylated IκB proteins in retinas from different groups. (b–e) Quantification data from the western blots after normalizing to β-actin. , , and when compared with the ND group. ND, nondiabetic group; D4/D8/D12, diabetic group at 4, 8, and 12 weeks; DM4/DM8/DM12, melatonin-treated diabetic group at 4, 8, and 12 weeks.

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