Is Liver Enzyme Release Really Associated with Cell Necrosis Induced by Oxidant Stress?

Figure 2

Effects of changing the oxidative status on enzyme release from isolated liver mitochondria from control and PH rats. Results are expressed as mean ± SE of four individual observations per experimental point and correspond to the percentage of the released enzyme in respect to the total mitochondrial activity for each enzyme. Bas: basal, Subs: substrates, H₂O₂: hydrogen peroxide, and BHT: butylated hydroxytoluene. Statistical significance: against the group of sham-operated controls (incubated with substrates); versus PH rats group (incubated with substrates).

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