Research Article
PD98059 Protects Brain against Cells Death Resulting from ROS/ERK Activation in a Cardiac Arrest Rat Model
Table 4
The MDA and SOD activity levels in brain after ROSC.
| | Group | | 12 h | 24 h | 48 h | 72 h | | MDA levels (U/mg prot) | SOD activity (nmol/mg prot) | MDA levels (U/mg prot) | SOD activity (nmol/mg prot) | MDA levels (U/mg prot) | SOD activity (nmol/mg prot) | MDA levels (U/mg prot) | SOD activity (nmol/mg prot) |
| | Sham | 6 | 4.67 ± 0.66 | 120.67 ± 8.96 | 4.67 ± 0.66 | 120.67 ± 8.96 | 4.67 ± 0.66 | 120.67 ± 8.96 | 4.67 ± 0.66 | 120.67 ± 8.96 | | CA | 24 | 7.47 ± 6.01 | 75.16 ± 4.85 | 8.38 ± 0.75 | 61.65 ± 8.56 | 10.19 ± 0.70 | 54.13 ± 5.81 | 7.50 ± 0.729 | 60.67 ± 7.17 | | PD | 24 | 5.82 ± 0.80 | 97.33 ± 7.02 | 8.18 ± 0.84 | 70.60 ± 8.47 | 5.19 ± 0.62 | 84.12 ± 7.21 | 5.03 ± 0.71 | 83.24 ± 7.03 |
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and compared to the sham group; compared to CA group ().
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