Virus Infections on Prion Diseased Mice Exacerbate Inflammatory Microglial Response

Table 4

CA1 microglial numbers in the stratum radiatum of CA1 from animals injected with normal brain homogenate (NBH) or NBH followed by Piry intranasal injection or with ME7 infected brain homogenate (ME7) or by ME7 followed by Piry virus intranasal injection.

Stratum radiatum of CA1
Subjects		Thickness (μm)	CE (Scheaffer)
NBH
NBHVII-2	7877.17	29.2	0.05
NBHVII-3	5718.76	18.2	0.06
NBHVII-4	6755.67	19.0	0.05
Mean	6784	22.1	0.05
SD	1079
CV^2	0.025
CE^2	0.003
CE^2/CV^2	0.113
CVB^2	0.022
CVB^2 (% CV^2)	89
NBH+VIRUS
NBHV-3	8560.43	18.8	0.05
NBHVI-1	5478.32	15.0	0.05
NBHVI-2	6818.47	17.5	0.05
NBHVI-4	8078.08	18.1	0.04
Mean	7234	17.4	0.05
SD	1382
CV^2	0.036
CE^2	0.002
CE^2/CV^2	0.064
CVB^2	0.034
CVB^2 (% CV^2)	93.6
ME7
ME7IX-1	12363.62	22.5	0.05
ME7IX-4	11988.17	15.9	0.04
ME7X-2	15181.15	19.4	0.04
ME7X-4	8953.73	22.6	0.06
Mean	12122	20.1	0.05
SD	2548
CV^2	0.044
CE^2	0.002
CE^2/CV^2	0.053
CVB^2	0.042
CVB^2 (% CV^2)	95
ME7+VIRUS
ME7VII-1	28541.47	21.9	0.04
ME7VII-4	19120.84	15.2	0.04
ME7VIII-1	21131.22	21.4	0.04
ME7VIII-4	17769	20.8	0.05
Mean	21641	19.8	0.04
SD	4803
CV^2	0.049
CE^2	0.002
CE^2/CV^2	0.034
CVB^2	0.048
CVB^2 (% CV^2)	97

CVB² = (CV, coefficient of variation; CE, Scheaffer coefficient of error; CVB, biological variation coefficient).