High-Fat Diet Induces Oxidative Stress and MPK2 and HSP83 Gene Expression in Drosophila melanogaster

Figure 3

Effects of the exposure to a high-fat diet on locomotor performance and acetylcholinesterase (AChe) activity in D. melanogaster. (a) Locomotor ability of flies was analyzed by negative geotaxis after seven days of exposure to coconut oil enriched diet (0%, 10%, and 20%). Three sets of ten flies were used for each diet condition. Results are expressed as mean of time spent to reach 8 cm in a glass tube ± SE of three independent experiments. (b) The data shows the AChe activity in flies’ homogenate expressed as mean (mU/mg protein) ± standard deviation. Three sets of twenty flies were analyzed for each diet condition. indicates a significant difference in the RD and the HFD ().

(a)

(b)