Colonic and Hepatic Modulation by Lipoic Acid and/or N-Acetylcysteine Supplementation in Mild Ulcerative Colitis Induced by Dextran Sodium Sulfate in Rats

Figure 7

Hepatic redox markers: superoxide dismutase (SOD) activity (a); catalase activity (b); glutathione peroxidase (GPx) activity (c); reduced glutathione (GSH) levels (d); malondialdehyde (MDA) levels (e); hydrogen peroxide (H₂O₂) levels (f); myeloperoxidase (MPO) activity (g); nitrite levels (h); glutathione oxidized (GSSG) levels (i); and GSH/GSSG ratio (j), according to group: control; mild colitis; lipoic acid, LA; N-acetylcysteine, NAC; LA associated with NAC − LA + NAC. (Tukey test). (Tukey test). Ps.: GSSG (Kruskal-Wallis test).

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)

(j)