The Coadministration of N-Acetylcysteine Ameliorates the Effects of Arsenic Trioxide on the Male Mouse Genital System

Table 2

Sperm counts of control and treated animals.

Parameters	Control ()	0.3 mg/kg ()	3.0 mg/kg ()
105-day-old mouse
Sperm head count (×10^6/testis)	22.53 ± 0.85	21.12 ± 0.84	16.11 ± 0.53
Sperm head count (×10^6/g testis)	218.70 ± 11.35	205.50 ± 10.59	161.70 ± 9.40
Daily sperm production (×10^6/testis)	4.65 ± 0.18	4.36 ± 0.17	3.32 ± 0.11
Daily sperm production (×10^6/g testis)	45.19 ± 0.18	42.44 ± 2.19	33.37 ± 1.95
155-day-old mouse
Sperm head count (×10^6/testis)	22.11 ± 1.29	23.67 ± 1.15	14.13 ± 1.00
Sperm head count (×10^6/g testis)	242.8 ± 12.63	304.3 ± 26.53	241.3 ± 22.77
Daily sperm production (×10^6/testis)	4.56 ± 0.27	4.98 ± 0.23	3.53 ± 0.21
Daily sperm production (×10^6/g testis)	50.11 ± 2.61	62.89 ± 5.57	49.73 ± 4.73

Values expressed as mean + SEM. One-way analysis of variance (ANOVA) test, followed by Tukey’s test.
Different letters indicate groups that differ at 5% significance level.