The Coadministration of N-Acetylcysteine Ameliorates the Effects of Arsenic Trioxide on the Male Mouse Genital System

Table 3

Sperm counts in controls and animals treated with 3.0 mg/Kg of As₂O₃, 40 mM of NAC, and both As₂O₃ and NAC.

Parameters	Control ()	As2O3 ()	NAC ()	NAC + As2O3 ()
Sperm head count (×10^6/testis)	21.89 ± 1.06	16.96 ± 0.71	22.25 ± 1.24	21.97 ± 1.29
Sperm head count (×10^6/g testis)	199.50 ± 6.55	150.90 ± 9.25	198.9 ± 7.09	214.70 ± 12.85
Daily sperm production (×10^6/testis)	4.52 ± 0.22	3.50 ± 0.15	4.59 ± 0.26	4.54 ± 0.26
Daily sperm production (×10^6/g testis)	41.22 ± 1.36	31.08 ± 1.83	41.06 ± 1.46	44.34 ± 2.65

Values expressed as mean + S.E.M. One-way analysis of variance (ANOVA) test, followed by Tukey test.
Different letters indicate groups that differ at 5% significance level.