PTEN Activation by DNA Damage Induces Protective Autophagy in Response to Cucurbitacin B in Hepatocellular Carcinoma Cells

Figure 9

PTEN activation by DNA damage mediated autophagy in response to Cuc B. PTEN was silenced followed by treatment with Cuc B for 6 h and the DNA damage and protein expression were determined by comet assay (a) and Western blot (b and e). ATM or Chk1 was silenced followed by treatment with Cuc B for 6 h and the protein expression was determined by Western blot (c and d).

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