Elevated Levels of Urinary Markers of Oxidative DNA and RNA Damage in Type 2 Diabetes with Complications

Table 2

Urinary levels of 8-oxodGuo and 8-oxoGuo in the different age group.

	Age group
	31–40 (years)	41–50 (years)	51–60 (years)	61–70 (years)	71–80 (years)	All 31–80 (years)
8-oxodGuo (μmol/mol creatinine)
Healthy controls	1.27 ± 0.58	1.25 ± 0.56	1.73 ± 0.76	2.02 ± 0.95	2.02 ± 1.04	1.68 ± 0.87
Diabetes without complications	1.48 ± 0.62	1.65 ± 0.86	1.80 ± 1.01	1.80 ± 1.04	1.84 ± 1.07	1.75 ± 0.97
Diabetes with complications	1.53 ± 0.96	1.67 ± 1.00	1.84 ± 0.98	1.62 ± 0.97	1.75 ± 0.81	1.70 ± 0.95
8-oxoGuo (μmol/mol creatinine)
Healthy controls	1.65 ± 0.47	1.81 ± 0.55	2.22 ± 0.72	2.58 ± 0.88	2.82 ± 0.86	2.25 ± 0.84
Diabetes without complications	2.09 ± 0.78	2.19 ± 0.97	2.64 ± 1.04	2.63 ± 1.08	3.07 ± 1.29	2.55 ± 1.10
Diabetes with complications	2.45 ± 1.67	2.38 ± 1.01	3.01 ± 1.32	2.70 ± 1.17	3.34 ± 1.24	2.81 ± 1.27