Redox Modulations, Antioxidants, and Neuropsychiatric Disorders

Figure 4

Mechanisms of action of exogenous antioxidants. Red: enzymes; green: other products; purple: cofactor/substrate; black: reactive species; CAT, catalase; MC, metal chelator; POH, polyphenol; GSSG, oxidized glutathione; MPO, myeloperoxidase. Reaction legend 1A: H-atom transfer, 1B: electron donation, 1C: direct scavenging, 2: metal chelation, 3: restoration of endogenous antioxidants, 4: inhibition of RS generating species and reactions, 5: support of endogenous antioxidant enzymes, 6: cofactor in antioxidant enzymes, 7: singlet oxygen quenching.