Redox Nanoparticle Therapeutics for Acetaminophen-Induced Hepatotoxicity in Mice

Figure 7

Hepatoprotective effect of treatments in mice with APAP-induced liver damage. (a) control group. (b) APAP-induced group. ((c)–(f)) APAP group treated with (c) 600 mg/kg BW of NAC, (d) 15.4 mM of LMW TEMPO, (e) 12.5 mg/mL of nRNP, (f) and 12.5 mg/mL of . Liver sections were stained with hematoxylin and eosin (400). CV: central vein; S: sinusoids; KC; Kupffer cell; N: necrosis; I: inflammation; H: hemorrhage.

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