Protective Role of Dietary Curcumin in the Prevention of the Oxidative Stress Induced by Chronic Alcohol with respect to Hepatic Injury and Antiatherogenic Markers

Figure 2

Influence of chronic ethanol, ω-3 PUFA, and curcumin on serum ALT and AST in rats fed low and high ω-3 PUFA diets. The animals in the indicated groups () were pair-fed their respective Lieber-DeCarli alcohol containing liquid diets supplemented with the indicated concentration of curcumin for 8 weeks after which the animals were killed and each serum sample was analyzed. (a) ALT and (b) AST levels of these liver markers were measured as described in Section 2. The relative ALT and AST activities in the various experimental groups are expressed as international units per liter. The data are Means ± SEM. Statistical significance of variance was calculated using t-test with Bonferroni correction; compared to LFO group; compared to the corresponding LFOE group; compared to HFO group; compared to HFOE group.

(a)

(b)