Endothelial Microparticle-Derived Reactive Oxygen Species: Role in Endothelial Signaling and Vascular Function

Figure 3

Effects of endothelial MPs on phosphorylation of eNOS in cultured mouse aortic ECs. ECs were exposed to endothelial MPs (10⁵/mL) and phosphorylation of eNOS at activation site, residue serine 1177 (a), and inhibitory site, residue threonine 495 (b), was examined by Western blot analysis. versus no treatment (0 hours), –6.

(a)

(b)