Lung Neutrophilia in Myeloperoxidase Deficient Mice during the Course of Acute Pulmonary Inflammation

Figure 1

Acute lung inflammation induces accumulation of neutrophils in lungs. (a) Total nucleated cell counts, (b) relative count of airway macrophages, (c) relative count of neutrophils, and (d) total neutrophils in BALF collected at various times (8 h, 24 h, 48 h, and 72 h) after instillation of LPS (0.3 mg/kg) or PBS (control at time 0 h) in wild-type (WT; black bars) and MPO deficient (MPO KO; grey bars) mice. Values represent mean ± SEM from 8–10 mice with significant difference between WT and MPO KO mice ().

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