Role of TFEB Mediated Autophagy, Oxidative Stress, Inflammation, and Cell Death in Endotoxin Induced Myocardial Toxicity of Young and Aged Mice

Figure 1

Effect of LPS in young and aged mice on cardiac injury. Cardiac injury was measured by plasma LDH (a) and CK (b). Both enzymes were significantly increased in LPS treated mice. Increase of LPS induced cardiac injury in aged mice was significantly higher than young ones. Values represented as means ± SD; and = 6/group.

(a)

(b)