Notch1 Pathway Protects against Burn-Induced Myocardial Injury by Repressing Reactive Oxygen Species Production through JAK2/STAT3 Signaling

Figure 1

Notch1 pathway responds to myocardial injury after burn. Mice were subjected to burn injury. (a, c) Protein expression of Notch1 intracellular domain (NICD) and Hes1 in mouse myocardial tissue after burn injury over time. Rat cardiomyocytes were challenged with burn serum in vitro. (b, d) showed the NICD1 and Hes1 protein expression in cardiomyocytes. The values presented are the mean ± SEM ( per group). compared to the value in sham groups.

(a)

(b)

(c)

(d)