Notch1 Pathway Protects against Burn-Induced Myocardial Injury by Repressing Reactive Oxygen Species Production through JAK2/STAT3 Signaling

Figure 3

Notch signal deficiency exacerbates burn-induced myocardial injury in vivo. RBP-J KO or control mice were subjected to burn injury and were examined 12 hours or 24 hours after injury. Serum CK (a), CK-MB (b), and LDH (c). (d) Apoptotic cells were stained by TUNEL staining in myocardial tissues. (e) Quantitative comparison of apoptotic cells upon TUNEL staining in (d). The values presented are the mean ± SEM ( per group). .

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