Oxidative Medicine and Cellular Longevity / 2016 / Article / Tab 3

Research Article

Changes in Oxidative Stress and Inflammatory Biomarkers in Fragile Adults over Fifty Years of Age and in Elderly People Exclusively Fed Enteral Nutrition

Table 3

Blood oxidative stress parameters of frail adult and elderly patients fed exclusively by total enteral nutrition with the experimental and reference diets for 90 d and 180 d.

ExperimentalReference
Baseline ()90 d ()180 d ()Baseline ()90 d ()180 d ()

LDL susceptibility to oxidation
 Dienes lag Phase (min)78.1 ± 3.458.1 ± 3.071.5 ± 4.070.5 ± 3.067.67 ± 2.770.6 ± 4.6
 Dienes slope (mU OD/min)1.30 ± 0.091.56 ± 0.161.89 ± 0.241.26 ± 0.101.28 ± 0.121.82 ± 0.16
 LDL hydroperoxides2.67 ± 0.213.66 ± 0.343.26 ± 0.184.56 ± 0.313.61 ± 0.394.15 ± 0.31
 OxLDL (ng/mL)167.7 ± 26.7166.7 ± 25.2175.6 ± 28.9126.2 ± 12.5156.5 ± 29.6129.9 ± 14.1
DNA damage
 Comet head (%)72.8 ± 2.276.8 ± 2.175.6 ± 1.675.45 ± 2.078.7 ± 1.779.8 ± 1.8
 Comet tail (%)24.4 ± 1.627.2 ± 2.223.2 ± 2.120.2 ± 1.824.5 ± 2.121.3 ± 1.7
 Comet tail moment0.53 ± 0.050.60 ± 0.080.51 ± 0.070.37 ± 0.050.43 ± 0.050.37 ± 0.04

Significant difference between groups according to a general lineal model for repeated measures. Significant differences between groups at each time point. Mean values within a row with unlike superscript letters are significantly different in each group. < 0.05 was considered significant. LDL hydroperoxide units are nmol/mg LDL protein. LDL, low-density lipoprotein; OD, optical density; oxLDL, oxidized low-density lipoprotein.

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.