Review Article
Molecular Hydrogen Therapy Ameliorates Organ Damage Induced by Sepsis
Table 1
The impact of changes of the biochemistry indicator level.
| | | Brain | Lung | Liver | Kidney | Intestine |
| | Capase-3 | HRS | HRS | / | / | / | | SOD | HRS ,H2 | HRS | H2 | H2 | H2 | | ROS | H2, HRS | / | / | / | / | | MPA | H2, HRS | HRS | / | H2 | H2 | | CAT | HRS , H2 | HRS | H2 | H2 | / | | 8-iso-PGF2α | H2 | HRS | H2 | H2 | / | | Nrf2 | H2 | / | / | / | / | | TNF-α | H2 | HRS or | H2 | H2 | H2 | | IL-1β | H2 | HRS | / | / | / | | IL-6 | / | HRS | / | H2 | / | | IL-8 | / | HRS | / | H2 | / | | HMGB1 | H2 | HRS | H2 | / | H2 | | IL-10 | H2 | HRS or | H2 | H2 or | / | | MPO | / | HRS or | / | / | / | | Others | Cognitive impairment: HRS is less than sepsis group; HRS is similar to sham group | () W/D weight ratio: H2, HRS
() BALF cell counts: H2 | ALT, ACT: H2, HRS
H2 group is similar to sham group | BUN, Cr: H2 | DAO: H2 | | References | [7–9] | [5, 6, 10–12] | [5, 10, 11] | [5, 10, 11, 13] | [6] |
|
|
HRS: hydrogen-rich water injection or oral-taken group.
H2: H2 inhalation group.
SOD: superoxide dismutase.
CAT: catalase.
HMGB1: high mobility group box 1.
IL: interleukin.
W/D: wet/dry.
BALF: bronchoalveolar lavage fluid.
ALT: alanine aminotransferase.
|
