Fibroblast Growth Factor-9 Activates c-Kit Progenitor Cells and Enhances Angiogenesis in the Infarcted Diabetic Heart

Figure 6

FGF-9 enhances left ventricular function in post-MI C57BL/6 and db/db mice. Two weeks following MI or sham surgery, heart function was assessed using transthoracic 2D echocardiography. (a) Table includes calculated cardiac functional data for all control and experimental groups. Histograms demonstrate quantitative analysis of (b) LVIDd, (c) LVIDs, (d) % fractional shortening, (e) EDV, (f) ESV, and (g) % ejection fraction. LVIDd = left ventricular internal dimension-diastole, LVIDs = left ventricular internal dimension-systole, FS = fractional shortening, EDV = left ventricular volume at end diastole, ESV = left ventricular volume at end systole, and EF = ejection fraction. versus sham and versus MI.

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