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Oxidative Medicine and Cellular Longevity
Volume 2016, Article ID 5818479, 8 pages
http://dx.doi.org/10.1155/2016/5818479
Research Article

Antioxidant and Anti-Inflammatory Effects of Coenzyme Q10 on L-Arginine-Induced Acute Pancreatitis in Rat

1Department of Surgery, Islamic Azad University, Tehran Medical Sciences Branch, Tehran, Iran
2Students’ Research Committee, Islamic Azad University, Tehran Medical Sciences Branch, Tehran, Iran
3Young Researchers and Elite Club, Islamic Azad University, Tehran Medical Sciences Branch, Tehran, Iran
4Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
5Students’ Research Committee, Baqiyatallah University of Medical Sciences, Tehran, Iran

Received 12 January 2016; Revised 10 March 2016; Accepted 22 March 2016

Academic Editor: Giuseppe Cirillo

Copyright © 2016 Seyed Abbas Mirmalek et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. P. G. Lankisch, M. Apte, and P. A. Banks, “Acute pancreatitis,” The Lancet, vol. 386, no. 9988, pp. 85–96, 2015. View at Publisher · View at Google Scholar · View at Scopus
  2. A. F. Peery, E. S. Dellon, J. Lund et al., “Burden of gastrointestinal disease in the United States: 2012 update,” Gastroenterology, vol. 143, no. 5, pp. 1179–1187.e3, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. M. Ghorbani, M. Chavoshi-Nejad, T. Parsa et al., “The effect of atorvastatin on acute pancreatitis in rat: biochemical and Pathological study,” Galen Medical Journal, vol. 4, no. 1, pp. 56–58, 2015. View at Google Scholar
  4. D. M. Cruz-Santamaría, C. Taxonera, and M. Giner, “Update on pathogenesis and clinical management of acute pancreatitis,” World Journal of Gastrointestinal Pathophysiology, vol. 3, no. 3, p. 60, 2012. View at Google Scholar
  5. B. U. Wu, “Prognosis in acute pancreatitis,” Canadian Medical Association Journal, vol. 183, no. 6, pp. 673–677, 2011. View at Google Scholar
  6. J. Norman, “The role of cytokines in the pathogenesis of acute pancreatitis,” The American Journal of Surgery, vol. 175, no. 1, pp. 76–83, 1998. View at Publisher · View at Google Scholar · View at Scopus
  7. M. H. Schoenberg, M. Buchler, M. Gaspar et al., “Oxygen free radicals in acute pancreatitis of the rat,” Gut, vol. 31, no. 10, pp. 1138–1143, 1990. View at Publisher · View at Google Scholar · View at Scopus
  8. M. Abu-Hilal, M. J. W. McPhail, L. Marchand, and C. D. Johnson, “Malondialdehyde and superoxide dismutase as potential markers of severity in acute pancreatitis,” Journal of the Pancreas, vol. 7, no. 2, pp. 185–192, 2006. View at Google Scholar · View at Scopus
  9. I. M. Møller, “PLANT MITOCHONDRIA AND OXIDATIVE STRESS: electron transport, NADPH turnover, and metabolism of reactive oxygen species,” Annual Review of Plant Physiology and Plant Molecular Biology, vol. 52, pp. 561–591, 2001. View at Publisher · View at Google Scholar · View at Scopus
  10. O. Blokhina, E. Virolainen, and K. V. Fagerstedt, “Antioxidants, oxidative damage and oxygen deprivation stress: a review,” Annals of Botany, vol. 91, pp. 179–194, 2003. View at Publisher · View at Google Scholar · View at Scopus
  11. Z.-X. Bian and S.-W. Tsang, “Therapeutic implications of antioxidant defense in acute pancreatitis,” Hepatobiliary and Pancreatic Diseases International, vol. 13, no. 4, pp. 346–347, 2014. View at Publisher · View at Google Scholar · View at Scopus
  12. M. Esrefoglu, “Experimental and clinical evidence of antioxidant therapy in acute pancreatitis,” World Journal of Gastroenterology, vol. 18, no. 39, pp. 5533–5541, 2012. View at Publisher · View at Google Scholar · View at Scopus
  13. F. L. Crane, “Biochemical functions of coenzyme Q10,” Journal of the American College of Nutrition, vol. 20, no. 6, pp. 591–598, 2001. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Anwar, M. A. El-Moniem, H. A. Megahed, S. E. EL-Toukhy, N. A. Mohammed, and E. R. Youness, “Effect of coenzyme Q10 supplementation on markers of oxidative stress in streptozotocin induced diabetic rats,” Journal of Applied Pharmaceutical Science, vol. 4, no. 6, pp. 009–015, 2014. View at Publisher · View at Google Scholar
  15. O. H. Lowry, N. J. Rosebrough, A. L. Farr, and R. J. Randall, “Protein measurement with the Folin phenol reagent,” The Journal of Biological Chemistry, vol. 193, no. 1, pp. 265–275, 1951. View at Google Scholar · View at Scopus
  16. F. Tietze, “Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues,” Analytical Biochemistry, vol. 27, no. 3, pp. 502–522, 1969. View at Publisher · View at Google Scholar · View at Scopus
  17. E. Agar, M. Bosnak, R. Amanvermez, S. Demir, M. Ayyildiz, and C. Celik, “The effect of ethanol on lipid peroxidation and glutathione level in the brain stem of rat,” NeuroReport, vol. 10, no. 8, pp. 1799–1801, 1999. View at Publisher · View at Google Scholar · View at Scopus
  18. P. P. Bradley, D. A. Priebat, R. D. Christensen, and G. Rothstein, “Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker,” Journal of Investigative Dermatology, vol. 78, no. 3, pp. 206–209, 1982. View at Publisher · View at Google Scholar · View at Scopus
  19. J. Schmidt, D. W. Rattner, K. Lewandrowski et al., “A better model of acute pancreatitis for evaluating therapy,” Annals of Surgery, vol. 215, no. 1, pp. 44–56, 1992. View at Publisher · View at Google Scholar · View at Scopus
  20. M. Potgieter, E. Pretorius, and M. S. Pepper, “Primary and secondary coenzyme Q10 deficiency: the role of therapeutic supplementation,” Nutrition Reviews, vol. 71, no. 3, pp. 180–188, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. J. J. Sutachan, Z. Casas, S. L. Albarracin et al., “Cellular and molecular mechanisms of antioxidants in Parkinson's disease,” Nutritional Neuroscience, vol. 15, no. 3, pp. 120–126, 2012. View at Publisher · View at Google Scholar · View at Scopus
  22. S. Kardeh, S. Ashkani-Esfahani, and A. M. Alizadeh, “Paradoxical action of reactive oxygen species in creation and therapy of cancer,” European Journal of Pharmacology, vol. 735, no. 1, pp. 150–168, 2014. View at Publisher · View at Google Scholar · View at Scopus
  23. M. Schieber and N. S. Chandel, “ROS function in redox signaling and oxidative stress,” Current Biology, vol. 24, no. 10, pp. R453–R462, 2014. View at Publisher · View at Google Scholar · View at Scopus
  24. S. Navina, C. Acharya, J. P. DeLany et al., “Lipotoxicity causes multisystem organ failure and exacerbates acute pancreatitis in obesity,” Science Translational Medicine, vol. 3, no. 107, Article ID 107ra110, 2011. View at Publisher · View at Google Scholar
  25. W. R. Matull, S. P. Pereira, and J. W. O'Donohue, “Biochemical markers of acute pancreatitis,” Journal of Clinical Pathology, vol. 59, no. 4, pp. 340–344, 2006. View at Publisher · View at Google Scholar · View at Scopus
  26. M. Sendler, A. Dummer, F. U. Weiss et al., “Tumour necrosis factor α secretion induces protease activation and acinar cell necrosis in acute experimental pancreatitis in mice,” Gut, vol. 62, no. 3, pp. 430–439, 2013. View at Publisher · View at Google Scholar · View at Scopus
  27. J.-L. Van Laethem, R. Eskinazi, H. Louis, F. Rickaert, P. Robberecht, and J. Devière, “Multisystemic production of interleukin 10 limits the severity of acute pancreatitis in mice,” Gut, vol. 43, no. 3, pp. 408–413, 1998. View at Publisher · View at Google Scholar · View at Scopus
  28. J. Mayer, B. Rau, F. Gansauge, and H. G. Beger, “Inflammatory mediators in human acute pancreatitis: clinical and pathophysiological implications,” Gut, vol. 47, no. 4, pp. 546–552, 2000. View at Publisher · View at Google Scholar · View at Scopus
  29. A. K. Siriwardena, J. M. Mason, S. Balachandra et al., “Randomised, double blind, placebo controlled trial of intravenous antioxidant (n-acetylcysteine, selenium, vitamin C) therapy in severe acute pancreatitis,” Gut, vol. 56, no. 10, pp. 1439–1444, 2007. View at Publisher · View at Google Scholar · View at Scopus
  30. S. Meher, T. S. Mishra, P. K. Sasmal et al., “Role of biomarkers in diagnosis and prognostic evaluation of acute pancreatitis,” Journal of Biomarkers, vol. 2015, Article ID 519534, 13 pages, 2015. View at Publisher · View at Google Scholar
  31. J. C. Lv, G. Wang, S. H. Pan, X. W. Bai, and B. Sun, “Lycopene protects pancreatic acinar cells against severe acute pancreatitis by abating the oxidative stress through JNK pathway,” Free Radical Research, vol. 49, no. 2, pp. 151–163, 2015. View at Publisher · View at Google Scholar · View at Scopus
  32. L. Robles, N. D. Vaziri, S. Li et al., “Synthetic triterpenoid RTA dh404 (CDDO-dhTFEA) ameliorates acute pancreatitis,” Pancreas, 2015. View at Publisher · View at Google Scholar
  33. M. Bakır, F. Geyikoglu, S. Colak, H. Turkez, T. O. Bakır, and M. Hosseinigouzdagani, “The carvacrol ameliorates acute pancreatitis-induced liver injury via antioxidant response,” Cytotechnology, 2015. View at Publisher · View at Google Scholar · View at Scopus
  34. J. Milewski, G. Rydzewska, M. Degowska, M. Kierzkiewicz, and A. Rydzewski, “N-acetylcysteine does not prevent post-endoscopic retrograde cholangiopancreatography hyperamylasemia and acute pancreatitis,” World Journal of Gastroenterology, vol. 12, no. 23, pp. 3751–3755, 2006. View at Publisher · View at Google Scholar · View at Scopus
  35. B. Kuklinski, T. Zimmermann, and R. Schweder, “Decreasing mortality in acute pancreatitis with sodium selenite. Clinical results of 4 years antioxidant therapy,” Medizinische Klinik, vol. 90, pp. 36–41, 1995. View at Google Scholar · View at Scopus
  36. J. Ren, Z. Luo, F. Tian, Q. Wang, K. Li, and C. Wang, “Hydrogen-rich saline reduces the oxidative stress and relieves the severity of trauma-induced acute pancreatitis in rats,” Journal of Trauma and Acute Care Surgery, vol. 72, no. 6, pp. 1555–1561, 2012. View at Publisher · View at Google Scholar · View at Scopus