Review Article
Diagnostic, Prognostic, and Therapeutic Value of Circulating miRNAs in Heart Failure Patients Associated with Oxidative Stress
| MicroRNAs | Regulation | Sources | Association | Methods | Study population | Number of samples | Potential value | Reference |
| miR-208b, miR-208a, and miR-499 | Up | Serum and plasma | NT-proBNP | A miRNA array/qRT-PCR | Human | | Diagnostic/prognostic | [3, 20] | miR-423-5p | Up | Plasma | NT-proBNP | A miRNA array/qRT-PCR | Human | | Diagnostic | [24, 54] | miR-133 | Down | Plasma | NT-proBNP | qRT-PCR | Human | | Diagnostic | [55] | miR-103, miR-142-3p, miR-30b, and miR-342-3p | Down | Plasma | NT-proBNP | A miRNA array/qRT-PCR | Human | | Diagnostic | [56] | miR-126 | Down | Plasma | NT-proBNP | qRT-PCR | Human | | Diagnostic | [57] | miR-210 and miR-30a | Up | Serum | NT-proBNP | qRT-PCR | Human | | Diagnostic | [58] | miR-192 | Up | | | | | | Prognostic | [59] | miR-26b-5p, miR-145-5p, miR-92a-3p, miR-30e-5p, and miR-29a-3p | Up | Plasma | NT-proBNP | A miRNA array/qRT-PCR | Human | | Prognostic | [60] | miR-483-3p | Up | Plasma | NT-proBNP | Microarray assay | Human | | Prognostic | [61] |
|
|