Neoatherosclerosis after Drug-Eluting Stent Implantation: Roles and Mechanisms

Table 1

Different characteristics of NA between BMS and DES.

	Neointima of BMS	Neointima of DES
Tissue components	Smooth muscle cells and proteoglycans-rich extracellular matrix	Fibrin deposition; proteoglycan deposition; larger necrotic; calcified components; and less smooth muscle cells
Lipid-laden plaque	Small	Large
Inflammatory cell infiltration	Less Inflammatory cell infiltration	Many kinds of inflammatory cells: macrophages, multinucleated giant cells, lymphocytes, and granulocytes
Developing time	Slow (>1 year after stenting)	Rapid (<1 year after stenting)
Type of NA	Less of thin-cap NA	Thin-cap NA
Progression	Slow or disappeared	Growing
Prognosis	Relatively stable	High frequency of late stent failure