Isosteviol Sensitizes sarcK_ATP Channels towards Pinacidil and Potentiates Mitochondrial Uncoupling of Diazoxide in Guinea Pig Ventricular Myocytes

Figure 5

Effects of STV and pinacidil on action potential of guinea pig ventricular myocytes. (a) Representative AP curve of STV-preincubated and control ventricular myocytes. (b) and (c) Effects of STV on action potential duration at 90% of repolarization (APD₉₀) and resting membrane potential (RMP), respectively. (d) Effect of pinacidil on action potential of ventricular myocytes. (e) and (f) Effects of pinacidil on action potential duration at APD₉₀ and RMP, respectively. means and means .

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