Polyphenols as Modulator of Oxidative Stress in Cancer Disease: New Therapeutic Strategies

Figure 1

Dual prooxidant role of ROS level in cancer cells. Prooxidant mechanisms associated with different cellular ROS levels: high levels could induce DNA damage and cell death whereas low levels could induce epigenetic alterations and senescence-like growth arrest. In the figure the classical role of ROS scavengers as antioxidants is also reported.