CD36/Sirtuin 1 Axis Impairment Contributes to Hepatic Steatosis in ACE2-Deficient Mice

Figure 1

Body weight, WAT index and lipid profile in ACE2 mice. (a) Body weight (g); (b) WAT index (%) of WT and ACE2 mice at the age of 3 and 6 months; (c) white adipocyte diameter (μm); (d) total cholesterol (mg⋅dL⁻¹), (e) triglycerides, (mg⋅dL⁻¹), (f) nonesterified fatty acids (NEFA) (mmol⋅L⁻¹) in plasma of WT and ACE2 mice at the age of 3 and 6 months; (g) total lipids (g⋅g⁻¹ of faeces), (h) total cholesterol (mg⋅g⁻¹ of faeces), (i) triglycerides (mg⋅g of faeces⁻¹), and (j) NEFA (mmol⋅g of faeces⁻¹) in faeces of WT and ACE2 mice at the age of 6 months. Each bar graph represents the mean ± SEM. Student’s t test: ; ; .

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)

(j)