CD36/Sirtuin 1 Axis Impairment Contributes to Hepatic Steatosis in ACE2-Deficient Mice

Figure 2

Hepatic steatosis and liver function of ACE2 mice. (a) Immunofluorescence staining for adipophilin in the liver; (b) adipophilin quantification (% area/view field); (c) relative liver weight (%); (d) total cholesterol in liver (mg⋅g⁻¹ of liver); (e) triglycerides in liver (mg⋅g⁻¹ of liver); (f) nonesterified fatty acids (NEFA) in liver (mmol⋅g⁻¹ of liver); (g) alanine aminotransferase (ALT) in plasma (U⋅L⁻¹); (h) aspartate aminotransferase (AST) in plasma (U⋅L⁻¹) of WT and ACE2 mice at the age of 3 and 6 months. Each bar graph represents the mean ± SEM. Student’s t test: ;; .

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