Resveratrol Regulates Mitochondrial Biogenesis and Fission/Fusion to Attenuate Rotenone-Induced Neurotoxicity

Figure 1

RSV improved survival rate and motor ability of rats decreased by rotenone. (a) The survival rate of rats in the R group is reduced significantly compared to the control, and resveratrol pretreatment significantly improves the survival rate of rats exposed to rotenone compared to the R group. (b) The rate of motion is decreased in rats exposed to rotenone; however, the rate of motion is significantly increased in rats pretreated with resveratrol. (c) Rotenone leads to a decrease in motion time, and resveratrol pretreatment improved the decrease in motion time induced by rotenone. The results are presented as the mean ± S.E.M. (/group for survival rate; /group for motion ability). versus control group; versus R group; versus R group.

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