The Antiapoptosis Effect of Glycyrrhizate on HepG2 Cells Induced by Hydrogen Peroxide

Figure 1

Cell viability of HepG2 cells following different concentrations of GAS pretreatment prior to H₂O₂ exposure (1600 μM, 4 h) was measured by MTT assay. With increase of the concentration of H₂O₂, cell survival rate was gradually decreased, and with H₂O₂ (1600 μM) for 4 hours, its survival rate has been reduced to % compared to that of natural group. GAS groups (5 μg/mL, 25 μg/mL, and 125 μg/mL) alleviated the cytotoxicity of HepG2 cells induced by H₂O₂, and increased cell viability. The annotation ## indicates a value < 0.05 versus natural group; the annotation indicates a value < 0.01 versus H₂O₂ group.