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Oxidative Medicine and Cellular Longevity
Volume 2016, Article ID 6849758, 9 pages
http://dx.doi.org/10.1155/2016/6849758
Research Article

The Antiapoptosis Effect of Glycyrrhizate on HepG2 Cells Induced by Hydrogen Peroxide

Department of Pharmacology, Pharmacy School, Inner Mongolian Medical University, Jinshan Developing Zone, Hohhot, Inner Mongolia 010110, China

Received 17 April 2016; Revised 25 August 2016; Accepted 28 September 2016

Academic Editor: Javier Egea

Copyright © 2016 Miao Su et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. K. W. Kong, S. Mat-Junit, N. Aminudin et al., “Protective effects of the extracts of barringtonia racemosa shoots against oxidative damage in hepg2 cells,” PeerJ, vol. 4, Article ID e1628, 2016. View at Google Scholar
  2. Y. Zhang, D. Yuan, W. Yao et al., “Hyperglycemia aggravates hepatic ischemia reperfusion injury by inducing chronic oxidative stress and inflammation,” Oxidative Medicine and Cellular Longevity, vol. 2016, Article ID 3919627, 16 pages, 2016. View at Publisher · View at Google Scholar
  3. R. Voltan, P. Secchiero, F. Casciano, D. Milani, G. Zauli, and V. Tisato, “Redox signaling and oxidative stress: cross talk with TNF-related apoptosis inducing ligand activity,” The International Journal of Biochemistry & Cell Biology, 2016. View at Publisher · View at Google Scholar
  4. D. Martín, M. Salinas, N. Fujita, T. Tsuruo, and A. Cuadrado, “Ceramide and reactive oxygen species generated by H2O2 induce caspase-3-independent degradation of Akt/protein kinase B,” Journal of Biological Chemistry, vol. 277, no. 45, pp. 42943–42952, 2002. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Dumont, S. P. Hehner, T. G. Hofmann, M. Ueffing, W. Dröge, and M. L. Schmitz, “Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-κB,” Oncogene, vol. 18, no. 3, pp. 747–757, 1999. View at Publisher · View at Google Scholar · View at Scopus
  6. H. Jaeschke, “Reactive oxygen and mechanisms of inflammatory liver injury,” Journal of Gastroenterology and Hepatology, vol. 15, no. 7, pp. 718–724, 2000. View at Publisher · View at Google Scholar · View at Scopus
  7. D. L. Tribble, T. Y. Aw, and D. P. Jones, “The pathophysiological significance of lipid peroxidation in oxidative cell injury,” Hepatology, vol. 7, no. 2, pp. 377–386, 1987. View at Publisher · View at Google Scholar · View at Scopus
  8. K. K. Cole and J. R. Perez-Polo, “Poly(ADP-ribose) polymerase inhibition prevents both apoptotic-like delayed neuronal death and necrosis after H2O2 injury,” Journal of Neurochemistry, vol. 82, no. 1, pp. 19–29, 2002. View at Publisher · View at Google Scholar · View at Scopus
  9. R. P. Englert and E. Shacter, “Distinct modes of cell death induced by different reactive oxygen species: amino acyl chloramines mediate hypochlorous acid-induced apoptosis,” The Journal of Biological Chemistry, vol. 277, no. 23, pp. 20518–20526, 2002. View at Publisher · View at Google Scholar · View at Scopus
  10. G. Szabo, J. R. Wands, A. Eken et al., “Alcohol and hepatitis C virus-interactions in immune dysfunctions and liver damage,” Alcoholism: Clinical and Experimental Research, vol. 34, no. 10, pp. 1675–1686, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. X. Zhang and J. J. Lemastersn, “Translocation of iron from lysosomes to mitochondria during ischemia predisposes to injury after reperfusion in rat hepatocytes,” Free Radical Biology and Medicine, vol. 63, pp. 243–253, 2013. View at Publisher · View at Google Scholar · View at Scopus
  12. R. H. Bhogal, C. J. Weston, S. M. Curbishley, D. H. Adams, and S. C. Afford, “Autophagy: a cyto-protective mechanism which prevents primary human hepatocyte apoptosis during oxidative stress,” Autophagy, vol. 8, no. 4, pp. 545–558, 2012. View at Publisher · View at Google Scholar · View at Scopus
  13. M. M. Hafez, O. A. Al-Shabanah, N. O. Al-Harbi et al., “Association between paraoxonases gene expression and oxidative stress in hepatotoxicity induced by CCl4,” Oxidative Medicine and Cellular Longevity, vol. 2014, Article ID 893212, 12 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  14. K. Ikeda, “Glycyrrhizin injection therapy prevents hepatocellular carcinogenesis in patients with interferon-resistant active chronic hepatitis C,” Hepatology Research, vol. 37, no. 2, pp. S287–S293, 2007. View at Publisher · View at Google Scholar
  15. J.-J. Park, K.-H. Lim, and K.-H. Baek, “Annexin-1 regulated by HAUSP is essential for UV-induced damage response,” Cell Death & Disease, vol. 6, no. 2, Article ID e1654, 2015. View at Publisher · View at Google Scholar · View at Scopus
  16. S. Zhang, Q. Liu, Y. Liu, H. Qiao, and Y. Liu, “Zerumbone, a Southeast Asian ginger sesquiterpene, induced apoptosis of pancreatic carcinoma cells through p53 signaling pathway,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 936030, 8 pages, 2012. View at Publisher · View at Google Scholar · View at Scopus
  17. S. Yodkeeree, B. Sung, P. Limtrakul, and B. B. Aggarwal, “Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: evidence for an essential role of reactive oxygen species,” Cancer Research, vol. 69, no. 16, pp. 6581–6589, 2009. View at Publisher · View at Google Scholar · View at Scopus
  18. J.-J. Xu and Y.-L. Wang, “Propofol attenuation of hydrogen peroxide-mediated oxidative stress and apoptosis in cultured cardiomyocytes involves haeme oxygenase-1,” European Journal of Anaesthesiology, vol. 25, no. 5, pp. 395–402, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. S. Zhu, I. G. Stavrovskaya, M. Drozda et al., “Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice,” Nature, vol. 417, no. 6884, pp. 74–78, 2002. View at Publisher · View at Google Scholar · View at Scopus
  20. A. N. Torun, S. Kulaksizoglu, M. Kulaksizoglu, B. O. Pamuk, E. Isbilen, and N. B. Tutuncu, “Serum total antioxidant status and lipid peroxidation marker malondialdehyde levels in overt and subclinical hypothyroidism,” Clinical Endocrinology, vol. 70, no. 3, pp. 469–474, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. D. B. Zorov, C. R. Filburn, L. O. Klotz et al., “Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes,” Journal of Experimental Medicine, vol. 192, no. 7, pp. 1001–1014, 2000. View at Publisher · View at Google Scholar
  22. S. W. Ryter, P. K. Hong, A. Hoetzel et al., “Mechanisms of cell death in oxidative stress,” Antioxidants and Redox Signaling, vol. 9, no. 1, pp. 49–89, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. W. C. Earnshaw, L. M. Martins, and S. H. Kaufmann, “Mammalian caspases: structure, activation, substrates, and functions during apoptosis,” Annual Review of Biochemistry, vol. 68, pp. 383–424, 1999. View at Publisher · View at Google Scholar · View at Scopus
  24. B. Jiang, W. Xiao, Y. Shi, M. Liu, and X. Xiao, “Heat shock pretreatment inhibited the release of Smac/DIABLO from mitochondria and apoptosis induced by hydrogen peroxide in cardiomyocytes and C2C12 myogenic cells,” Cell Stress and Chaperones, vol. 10, no. 3, pp. 252–262, 2005. View at Publisher · View at Google Scholar · View at Scopus
  25. R. Sugioka, S. Shimizu, T. Funatsu et al., “BH4-domain peptide from Bcl-xL exerts anti-apoptotic activity in vivo,” Oncogene, vol. 22, no. 52, pp. 8432–8440, 2003. View at Publisher · View at Google Scholar · View at Scopus