Antioxidation Effect of Simvastatin in Aorta and Hippocampus: A Rabbit Model Fed High-Cholesterol Diet

Figure 4

Analysis of biochemical measurements in each group of rabbits; Simvastatin enhanced the antioxidant status in hippocampus and aorta and reduced oxidative stress. (a) Effects of Simvastatin on MDA in serum. (b) Levels of MDA in hippocampal tissues; (c) SOD in serum; (d) levels of SOD in hippocampal homogenate. (e) Activity of GSH-Px in rabbit hippocampus. (f) Activity of iNOS showed in hippocampal tissues. Data are presented as mean ± SD (). and ## indicate significant change from control and HCD groups, respectively, at ; # means compared to the HCD group using ANOVA followed by LSD as a one-ANOVA test.

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