Oxidation-Reduction Potential as a Biomarker for Severity and Acute Outcome in Traumatic Brain Injury

Table 3

Comparative values of the ROC analyses for icORP on day 4, ISS, AIS-head, and GCS at predicting acute outcome.

	icORP day 4	ISS	AIS-head	GCS
Cut-off for survival status	7.25 μC	>27	>4	8
ROC-AUC	0.87  (0.78–0.94)	0.78  (0.68–0.85)	0.73  (0.63–0.81)	0.54  (0.43–0.65)
Sensitivity; (% of poor acute outcomes)	33.33 (0.8–90.6)	33.33 (4.3–77.7)	50.0 (11.8–88.2)	40.0 (5.3–85.3)
Specificity; (% of good acute outcomes)	100 (95.2–100)	89.90 (82.0–95.0)	75.51 (65.8–83.6)	72.1 (61.4–81.2)
Positive predictive value	100 (2.5–100)	16.7 (2.1–48.4)	11.1 (2.4–29.2)	7.7 (0.9–25.1)
Negative predictive value	97.4 (90.9–99.7)	95.7 (89.2–98.8)	96.1 (89.0–99.2)	95.4 (87.1–99.0)
Accuracy	96%	87%	74%	70%
	78	104	104	91

95% confidence intervals. Significant AUC values, .