The Role of Metformin in Controlling Oxidative Stress in Muscle of Diabetic Rats

Figure 2

Analysis of biomarkers of oxidative stress in gastrocnemius muscle of nondiabetic and diabetic rats treated with insulin and/or metformin. Total antioxidant capacity (FRAP) (a) and lipid peroxidation (TBARS) (b). Nondiabetic (ND), diabetic (D), diabetic treated with insulin (D+I), diabetic treated with metformin (D+M), and diabetic treated with insulin and metformin (D+I+M). versus ND, versus D, and versus D+I.

(a)

(b)