The Role of Metformin in Controlling Oxidative Stress in Muscle of Diabetic Rats

Figure 4

Catalase (a) and SOD (b) protein content of gastrocnemius muscle of nondiabetic and diabetic rats treated with insulin and/or metformin. Nondiabetic (ND), diabetic (D), diabetic treated with insulin (D+I), diabetic treated with metformin (D+M), and diabetic treated with insulin and metformin (D+I+M). At the top of each graph is a representative image of the western blot assay. Bands representatives of 3 rats/group (total = 6 rats/group). versus ND, versus D, and versus D+I.

(a)

(b)