An Evaluation of Root Phytochemicals Derived from Althea officinalis (Marshmallow) and Astragalus membranaceus as Potential Natural Components of UV Protecting Dermatological Formulations

Figure 1

Median percentage DNA damage in the tail of comets derived from cultured human lung fibroblasts exposed to (a) Astragalus extracts without irradiation, (b) Astragalus extracts with 16 minutes of filtered xenon-mercury irradiation (UVA + visible light), (c) Althea extracts without irradiation, and (d) Althea extracts with 16 minutes of filtered xenon-mercury irradiation (UVA + visible light). W = whole extract, R = retentate, and F = filtrate collected from elution periods 1, 2, and 3. Bars indicate the 75 percentile of the data set. + indicates a statistically significant increase in damage () when compared with the corresponding control group without extract exposure. and indicate a statistically significant decrease in damage ( and , resp.) when compared with the no extract control group.

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