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Oxidative Medicine and Cellular Longevity
Volume 2016, Article ID 7367641, 8 pages
http://dx.doi.org/10.1155/2016/7367641
Research Article

Association of Nuclear Factor-Erythroid 2-Related Factor 2, Thioredoxin Interacting Protein, and Heme Oxygenase-1 Gene Polymorphisms with Diabetes and Obesity in Mexican Patients

1Department of Biology, National Autonomous University of Mexico (UNAM), 04510 Mexico City DF, Mexico
2Economy Department, Autonomous Metropolitan University-Iztapalapa, 09340 Mexico City, DF, Mexico
3Research Department, Regional Hospital “Lic. Adolfo López Mateos”, ISSSTE, 01030 Mexico City, DF, Mexico
4Molecular Biology Department, National Institute of Cardiology “Ignacio Chávez”, 14080 Mexico City, DF, Mexico
5Department of Immunology, National Institute of Respiratory Diseases “Ismael Cosío Villegas”, 14080 Mexico City, DF, Mexico
6Molecular Genetics Laboratory, National School of Anthropology and History, 14030 Mexico City, DF, Mexico

Received 4 January 2016; Revised 29 March 2016; Accepted 5 April 2016

Academic Editor: Silvana Hrelia

Copyright © 2016 Angélica Saraí Jiménez-Osorio et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. International Diabetes Federation, Diabetes Atlas, International Diabetes Federation, Brussels, Belgium, 7th edition, 2015, http://www.diabetesatlas.org.
  2. R. H. Eckel, S. E. Kahn, E. Ferrannini et al., “Obesity and type 2 diabetes: what can be unified and what needs to be individualized?” Diabetes Care, vol. 34, no. 6, pp. 1424–1430, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. S. Tyrovolas, A. Koyanagi, N. Garin et al., “Diabetes mellitus and its association with central obesity and disability among older adults: a global perspective,” Experimental Gerontology, vol. 64, pp. 70–77, 2015. View at Publisher · View at Google Scholar · View at Scopus
  4. M. Serrano-Rios, “Relationship between obesity and the increased risk of major complications in non-insulin-dependent diabetes mellitus,” European Journal of Clinical Investigation, vol. 28, supplement 2, pp. 14–18, 1998. View at Publisher · View at Google Scholar · View at Scopus
  5. S.-I. Yamagishi, S. Maeda, T. Matsui, S. Ueda, K. Fukami, and S. Okuda, “Role of advanced glycation end products (AGEs) and oxidative stress in vascular complications in diabetes,” Biochimica et Biophysica Acta—General Subjects, vol. 1820, no. 5, pp. 663–671, 2012. View at Publisher · View at Google Scholar
  6. Y.-J. Surh, J. K. Kundu, and H.-K. Na, “Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals,” Planta Medica, vol. 74, no. 13, pp. 1526–1539, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. X. Wang, H. Chen, J. Liu et al., “Association between the NF-E2 related factor 2 gene polymorphism and oxidative stress, anti-oxidative status, and newly-diagnosed type 2 diabetes mellitus in a Chinese population,” International Journal of Molecular Sciences, vol. 16, no. 7, pp. 16483–16496, 2015. View at Publisher · View at Google Scholar · View at Scopus
  8. A. S. Jiménez-Osorio, A. Picazo, S. González-Reyes, D. Barrera-Oviedo, M. E. Rodríguez-Arellano, and J. Pedraza-Chaverri, “Nrf2 and redox status in prediabetic and diabetic patients,” International Journal of Molecular Sciences, vol. 15, no. 11, pp. 20290–20305, 2014. View at Publisher · View at Google Scholar · View at Scopus
  9. J. Pi, L. Leung, P. Xue et al., “Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity,” The Journal of Biological Chemistry, vol. 285, no. 12, pp. 9292–9300, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. H.-Y. Cho, “Genomic structure and variation of nuclear factor (erythroid-derived 2)-like 2,” Oxidative Medicine and Cellular Longevity, vol. 2013, Article ID 286524, 24 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  11. Y. Shimoyama, Y. Mitsuda, N. Hamajima, and T. Niwa, “Polymorphisms of Nrf2, an antioxidative gene, are associated with blood pressure in Japanese,” Nagoya Journal of Medical Science, vol. 76, no. 1-2, pp. 113–120, 2014. View at Google Scholar · View at Scopus
  12. S. M. Figarska, J. M. Vonk, and H. M. Boezen, “NFE2L2 polymorphisms, mortality, and metabolism in the general population,” Physiological Genomics, vol. 46, no. 12, pp. 411–417, 2014. View at Publisher · View at Google Scholar · View at Scopus
  13. D. Ross and D. Siegel, “NAD(P)H:quinone oxidoreductase 1 (NQO1, DT-diaphorase), functions and pharmacogenetics,” Methods in Enzymology, vol. 382, pp. 115–144, 2004. View at Publisher · View at Google Scholar · View at Scopus
  14. J.-E. Chung, B. C. Chang, K. E. Lee, J. H. Kim, and H. S. Gwak, “Effects of NAD(P)H quinone oxidoreductase 1 polymorphisms on stable warfarin doses in Korean patients with mechanical cardiac valves,” European Journal of Clinical Pharmacology, vol. 71, no. 10, pp. 1229–1236, 2015. View at Publisher · View at Google Scholar · View at Scopus
  15. H.-Y. Shyu, C.-S. Fong, Y.-P. Fu et al., “Genotype polymorphisms of GGCX, NQO1, and VKORC1 genes associated with risk susceptibility in patients with large-artery atherosclerotic stroke,” Clinica Chimica Acta, vol. 411, no. 11-12, pp. 840–845, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. S. J. Han, E. S. Kang, H. J. Kim et al., “The C609T variant of NQO1 is associated with carotid artery plaques in patients with type 2 diabetes,” Molecular Genetics and Metabolism, vol. 97, no. 1, pp. 85–90, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. T. Ramprasath, P. S. Murugan, E. Kalaiarasan, P. Gomathi, A. Rathinavel, and G. S. Selvam, “Genetic association of Glutathione peroxidase-1 (GPx-1) and NAD(P)H:quinone oxidoreductase 1(NQO1) variants and their association of CAD in patients with type-2 diabetes,” Molecular and Cellular Biochemistry, vol. 361, no. 1-2, pp. 143–150, 2012. View at Publisher · View at Google Scholar · View at Scopus
  18. A. Martínez-Hernández, E. J. Córdova, O. Rosillo-Salazar et al., “Association of HMOX1 and NQO1 polymorphisms with metabolic syndrome components,” PLoS ONE, vol. 10, no. 5, Article ID e0123313, 2015. View at Publisher · View at Google Scholar · View at Scopus
  19. E. Y. Lee, Y. H. Lee, S. H. Kim et al., “Association between heme oxygenase-1 promoter polymorphisms and the development of albuminuria in type 2 diabetes: a case-control study,” Medicine, vol. 94, no. 43, article e1825, 2015. View at Publisher · View at Google Scholar
  20. R. Lin, W. Fu, W. Zhou et al., “Association of heme oxygenase-1 gene polymorphisms with essential hypertension and blood pressure in the Chinese Han population,” Genetic Testing and Molecular Biomarkers, vol. 15, no. 1-2, pp. 23–28, 2011. View at Publisher · View at Google Scholar · View at Scopus
  21. E. Junn, S. H. Han, J. Y. Im et al., “Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function,” The Journal of Immunology, vol. 164, no. 12, pp. 6287–6295, 2000. View at Publisher · View at Google Scholar · View at Scopus
  22. X. He and Q. Ma, “Redox regulation by nuclear factor erythroid 2-related factor 2: gatekeeping for the basal and diabetes-induced expression of thioredoxin-interacting protein,” Molecular Pharmacology, vol. 82, no. 5, pp. 887–897, 2012. View at Publisher · View at Google Scholar · View at Scopus
  23. M. M. J. van Greevenbroek, V. M. M.-J. Vermeulen, E. J. M. Feskens et al., “Genetic variation in thioredoxin interacting protein (TXNIP) is associated with hypertriglyceridaemia and blood pressure in diabetes mellitus,” Diabetic Medicine, vol. 24, no. 5, pp. 498–504, 2007. View at Publisher · View at Google Scholar · View at Scopus
  24. N. E. Ferreira, S. Omae, A. Pereira et al., “Thioredoxin interacting protein genetic variation is associated with diabetes and hypertension in the Brazilian general population,” Atherosclerosis, vol. 221, no. 1, pp. 131–136, 2012. View at Publisher · View at Google Scholar · View at Scopus
  25. J. Grimberg, S. Nawoschik, L. Belluscio, R. McKee, A. Turck, and A. Eisenberg, “A simple and efficient non-organic procedure for the isolation of genomic DNA from blood,” Nucleic Acids Research, vol. 17, no. 20, p. 8390, 1989. View at Publisher · View at Google Scholar · View at Scopus
  26. J. Zúñiga, N. Yu, R. Barquera et al., “HLA class I and class II conserved extended haplotypes and their fragments or blocks in mexicans: implications for the study of genetic diversity in admixed populations,” PLoS ONE, vol. 8, no. 9, Article ID e74442, 2013. View at Publisher · View at Google Scholar
  27. P. Sanz, V. Prieto, I. Flores, Y. Torres, M. López-Soto, and M. J. Farfán, “Population data of 13 STRS in southern Spain (Andalusia),” Forensic Science International, vol. 119, no. 1, pp. 113–115, 2001. View at Publisher · View at Google Scholar · View at Scopus
  28. P. Calzada, I. Suárez, S. García et al., “The Fang population of Equatorial Guinea characterised by 15 STR-PCR polymorphisms,” International Journal of Legal Medicine, vol. 119, no. 2, pp. 107–110, 2005. View at Publisher · View at Google Scholar · View at Scopus
  29. C. Barrot, C. Sánchez, M. Ortega et al., “Characterisation of three Amerindian populations from Hidalgo State (Mexico) by 15 STR-PCR polymorphisms,” International Journal of Legal Medicine, vol. 119, no. 2, pp. 111–115, 2005. View at Publisher · View at Google Scholar · View at Scopus
  30. A. González-Martín, A. Gorostiza, H. Rangel-Villalobos et al., “Analyzing the genetic structure of the Tepehua in relation to other neighbouring Mesoamerican populations. A study based on allele frequencies of STR markers,” American Journal of Human Biology, vol. 20, no. 5, pp. 605–613, 2008. View at Publisher · View at Google Scholar · View at Scopus
  31. Y. Tan, T. Ichikawa, J. Li et al., “Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivo,” Diabetes, vol. 60, no. 2, pp. 625–633, 2011. View at Publisher · View at Google Scholar · View at Scopus
  32. H.-A. Seo and I.-K. Lee, “The role of NRF2: adipocyte differentiation, obesity, and insulin resistance,” Oxidative Medicine and Cellular Longevity, vol. 2013, Article ID 184598, 7 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  33. J. Xu, A. C. Donepudi, V. R. More et al., “Deficiency in Nrf2 transcription factor decreases adipose tissue mass and hepatic lipid accumulation in leptin-deficient mice,” Obesity, vol. 23, no. 2, pp. 335–344, 2015. View at Publisher · View at Google Scholar · View at Scopus
  34. A. Uruno, Y. Yagishita, and M. Yamamoto, “The Keap1-Nrf2 system and diabetes mellitus,” Archives of Biochemistry and Biophysics, vol. 566, pp. 76–84, 2015. View at Publisher · View at Google Scholar · View at Scopus
  35. G. Wang, L. Zhang, and Q. Li, “Genetic polymorphisms of GSTT1, GSTM1, and NQO1 genes and diabetes mellitus risk in Chinese population,” Biochemical and Biophysical Research Communications, vol. 341, no. 2, pp. 310–313, 2006. View at Publisher · View at Google Scholar · View at Scopus
  36. D. Kim, “An association between 609 C→T Polymorphism in NAD(P)H:quinone oxidoreductase 1 (NQO1) gene and blood glucose levels in Korean population,” Korean Diabetes Journal, vol. 33, no. 1, pp. 24–30, 2009. View at Publisher · View at Google Scholar
  37. S. K. Das, N. K. Sharma, S. J. Hasstedt et al., “An integrative genomics approach identifies activation of thioredoxin/thioredoxin reductase-1-mediated oxidative stress defense pathway and inhibition of angiogenesis in obese nondiabetic human subjects,” The Journal of Clinical Endocrinology & Metabolism, vol. 96, no. 8, pp. E1308–E1313, 2011. View at Publisher · View at Google Scholar · View at Scopus
  38. G. Tanaka, F. Aminuddin, L. Akhabir et al., “Effect of heme oxygenase-1 polymorphisms on lung function and gene expression,” BMC Medical Genetics, vol. 12, article 117, 2011. View at Publisher · View at Google Scholar · View at Scopus
  39. Y. Shimoyama, Y. Mitsuda, Y. Tsuruta, N. Hamajima, and T. Niwa, “Polymorphism of Nrf2, an antioxidative gene, is associated with blood pressure and cardiovascular mortality in hemodialysis patients,” International Journal of Medical Sciences, vol. 11, no. 7, pp. 726–731, 2014. View at Publisher · View at Google Scholar · View at Scopus